tert-butyl 4-(bromomethyl)-6-chlorobenzimidazole-1-carboxylate - Names and Identifiers
tert-butyl 4-(bromomethyl)-6-chlorobenzimidazole-1-carboxylate - Physico-chemical Properties
tert-butyl 4-(bromomethyl)-6-chlorobenzimidazole-1-carboxylate - Introduction
Acid, 4 bromomethyl)-6-chloro-, 1,1-dimethyllethyl ester (bromomethyl, 4-(6-chloro-, 1,1-dimethyllethyl ester) is an organic compound. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
-Chemical formula: C13H13BrClN2O2
-Molecular weight: 336.61g/mol
-Appearance: White crystalline solid
-Melting point: 102-104°C
-Boiling Point: 431.7°C at 760 mmHg
-Solubility: Soluble in some organic solvents, such as dichloromethane, dimethyl sulfoxide and dimethylformamide.
Use:
Acid, 4-(bromomethyl)-6-chlorophyll-, 1,1-dimethylethyl ester is an intermediate compound commonly used in organic synthesis. It can be used for the synthesis of biologically active compounds, for example, for the synthesis of antiviral, anti-tumor drugs.
Method:
The preparation method of acid, 4-(bromomethyl)-6-chloro-, 1,1-dimethylethyl ester is relatively complicated and requires a multi-step reaction. A possible synthesis method is to first react benzimidazole and tin tetrachloride to give 4-chloro-N-Boc-benzimidazole, and then react dibromomethane and iminodimethanol to obtain the target product.
Safety Information:
As a result, 4-(bromomethyl)-6-chlorine-, 1,1-dimethylethyl ester is an organic bromine compound, it may have certain toxicity and irritation. When using or handling the compound, care should be taken to comply with relevant safety procedures and avoid direct contact with skin, eyes and respiratory tract. In addition, the compound should be stored in a dry, cool place, away from open flames and high temperatures.
Last Update:2024-04-09 21:04:16